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  • Title: Demonstration of immunoglobulin on the surface of thymus lymphocytes.
    Author: Santana V, Wedderburn N, Turk JL.
    Journal: Immunology; 1974 Jul; 27(1):65-73. PubMed ID: 4604297.
    Abstract:
    Immunoglobulin molecules on the surface of mouse thymus cells have been shown by immunofluorescence. Ninety-five to 100 per cent of thymus lymphocytes were found to bind polyvalent rabbit anti-mouse immunoglobulin, although the density of the fluorescence was much less than that on the surface of B lymphocytes derived from the spleen. Two purified antisera, an anti-IgM and an anti-kappa chain serum, also stained the cells. The resynthesis of these immunoglobulin molecules in vitro was demonstrated after they had been removed with pronase.
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