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  • Title: A new transfer RNA fragment reaction: Tp psi pCpGp bound to a ribosome-messenger RNA complex induces the synthesis of guanosine tetra- and pentaphosphates.
    Author: Richter D, Erdmann VA, Sprinzl M.
    Journal: Proc Natl Acad Sci U S A; 1974 Aug; 71(8):3226-9. PubMed ID: 4606128.
    Abstract:
    The tetranucleotide TpPsipCpGp, when bound to Escherichia coli 50S ribosomal subunits, can replace intact tRNA in the stringent factor-directed synthesis of guanosine tetra- and pentaphosphates. The TpPsipCpGp-dependent fragment reaction has a strict requirement for the 50S and 30S ribosomal subunits and synthetic or natural messenger RNA.
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