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Title: Class of phi chi 174 mutants relatively deficient in synthesis of viral RNA. Author: Clements JB, Sinsheimer RL. Journal: J Virol; 1974 Dec; 14(6):1630-2. PubMed ID: 4610194. Abstract: Nonpermissive cells infected with phiX174 gene D amber mutants synthesized some sixfold less viral RNA than permissive cells. The decrease was unaffected by increasing the multiplicity of infection and was a consequence of an overall decrease in all viral RNA species. It is suggested that the gene D product may function in replicative form DNA unwinding to expose the template for transcription.[Abstract] [Full Text] [Related] [New Search]