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Title: [Prilocaine as an hypotensive ocular agent (author's transl)]. Author: Arbex ST, Neder AC, de Mattos Filho TR, Ramos AO. Journal: Rev Bras Pesqui Med Biol; 1979 Apr; 12(1):1-6. PubMed ID: 461853. Abstract: The purpose of the present investigation was to determine the action of prilocaine as hypotensive ocular agent. Prilocaine in doses of 2.5 mg/kg, 5 mg/kg and 10 mg/kg was administered intravenously in dogs anesthetized with sodium pentobarbital (30 mg/kg). The experiments show that prilocaine when used i.v. in doses of 2.5 mg/kg and 5 mg/kg causes ocular hypotension in dogs, whereas doses of 10 mg/kg i.v. produce this effect only when artificial respiration is employed, thus preventing the increase of the pCO2 in the blood.[Abstract] [Full Text] [Related] [New Search]