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  • Title: Plasma lecithin: cholesterol acyltransferase activity in normal full-term newborn infants.
    Author: Cisternas JR, Llanos A, Celedon JM, Riquelme R.
    Journal: Rev Bras Pesqui Med Biol; 1979 Apr; 12(1):9-15. PubMed ID: 461860.
    Abstract:
    Plasma lecithin: cholesterol acyltransferase (LCAT) activity was studied in 100 normal full-term newborn infants during the first few days of life. The present study shows that plasma LCAT activity present at birth-though at much lower levels than those in the maternal blood-undergoes a fall after birth followed by a rise. It is also shown that the activity of the plasma LCAT enzyme is not strictly linked to the esterification of plasma-free cholesterol in the first three days after birth. However, from the fourth day onwards, there was a good correlation between LCAT activity and esterification of plasma-free cholesterol. The results suggest that plasma LCAT in newborn infants could be partially derived from maternal sources.
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