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  • Title: Decrease of testosterone, cholesterol and ascorbic acid in the rat testis after administration of pineal polypeptides.
    Author: Damian E, Ianăş O, Bădescu I.
    Journal: Endocrinologie; 1979; 17(2):109-11. PubMed ID: 462106.
    Abstract:
    Administration of 2 ml/day/animal, of melatonin-free pineal extract to the rat for three days induced a significant decrease in the testicular tissue concentration of testosterone, cholesterol and ascorbic acid. A dose of 1 microgram melatonin/day/animal given for 3 days did not alter these biochemical elements implied in testicular steroidogenesis.
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