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  • Title: Antiglobulin factors in normal mouse serum reacting with enzyme-digested gamma globulin.
    Author: Measel JW, Cozad GC.
    Journal: Infect Immun; 1975 Feb; 11(2):290-3. PubMed ID: 46216.
    Abstract:
    The presence of antiglobulin factors in normal mouse serum was studied. Mice were injected with human 0 Rh(+) erythrocytes and the resulting gamma globulins were digested with papain. The reaction was demonstrated by agglutinations of human 0 Rh (+) perythryocytes sensitized with the Fab fragments when treated with normal mouse serum. Studies suggested that there are two factors in mice, a 7S AND A 19S globulin form. Cross-reactivity between strains of mice was demonstrated.
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