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  • Title: Antigenic relationship between the fourth component of human and guinea pig complement.
    Author: Ohanian SH, Borsos T.
    Journal: J Immunol; 1975 Jan; 114(1 Pt 1):161-4. PubMed ID: 46239.
    Abstract:
    Antigenic similarity between cell-bound human and guinea pig C4 was detected with antisera specific for each of these molecules. No cross-reaction could be detected between C4 of normal guinea pig or human sera or after treatment of the sera with antigen-antibody C1 complexes. The cross-reactivity between cell-bound human and guinea pig C4 may reflect conformational changes in the C4 molecule as a result of binding of the cell surface.
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