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  • Title: [Pathohistologic and biochemical changes in the brain in atherosclerotic dementia].
    Author: Vakulenko NN.
    Journal: Zh Nevropatol Psikhiatr Im S S Korsakova; 1979; 79(7):933-6. PubMed ID: 465164.
    Abstract:
    The data obtained from studies of 48 postmortem cases of atherosclerotic dementia with the use of histological and biochemical methods demonstrated a prevalence of ischemic changes in the nervous cells, cells-shadows, demyelinization, fragmentation of nervous filaments, hyperplasia, hypertrophy of astrocytes, a swelling of oligodendroglia compared to other changes. A drop in the amount of lecithin in the brain is the highest, while that in kefaline fractions is the lowest. A drop in the amount of sphyngomyelin occupies a middle place.
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