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  • Title: [Characteristics of the development of acute toxic hepatitis in rats stimulated with prodigiozan].
    Author: Maianskiĭ DN, Kutina SN.
    Journal: Biull Eksp Biol Med; 1979 Jun; 87(6):622-4. PubMed ID: 465705.
    Abstract:
    Acute toxic hepatitis was induced in Wistar rats by means of a single injection of 40% CCl4 on a peach-kernell oil base (0.2 ml/100 g body weight). Under conditions of stimulation with the bacterial polysaccharide prodigiosan, the resistance of hepatocytes to CCl4 sharply increased, which was shown by diminished severity of hepatic parenchyma destruction.
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