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  • Title: Computer-aided analysis of chromosomal aberrations occurring in an abnormal human karyotype.
    Author: Hazout S, Venuat AM, Valleron AJ, Rosenfeld C.
    Journal: Hum Genet; 1979 Jun 19; 49(2):133-45. PubMed ID: 468244.
    Abstract:
    A semi-automatic method for recognition of chromosomal changes is presented: from a coded description of an abnormal chromosome (formulated with the aid of an R-banding technique), a computer program makes simulations to reconstitute this chromosomal image from a group of normal chromosomes. Nine types of aberrations (see text) can thus be recognized and the aggregate structure of a group of abnormal chromosomes occurring in a human karyotype can also be rediscovered.
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