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  • Title: [Surgery of acute aortic dissection by use of a biological glue. Experimental study (author's transl)].
    Author: Laurian C, Gigou F, Bical O, Barbagelata M, Bachet J, Goudot B, Guilmet D.
    Journal: J Chir (Paris); 1979 Feb; 116(2):143-8. PubMed ID: 468928.
    Abstract:
    The improvement in surgical technic in the treatment of dissecting aneurysm of the aorta should permit a reduction in mortality and secondary complications. With this object, an attempt to stick together the two parts of the aneurysm with biological glue, was submitted to an experimental study. The operative protocol included on the one hand, creation of a dissecting aneurysm in the thorax of the dog, and secondly, repair of the latter with biological glue of variable composition. 27 dogs were thus operated on : -- 4 dissections were treated by simple suture (control group); -- in 23 cases, the two parts of the dissecting aneurysm were stuck together with gelatin-resorcin glue which was polymerised either by formaldehyde alone, or by a mixture of glutaraldehyde-glycerinaldehyde or by a mixture formaldehyde-glutaraldehyde. The best results of adhesiveness and tissue tolerance were obtained with the latter mixture.
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