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  • Title: The respiratory action of phenyl diguanide in vagotomized rabbits.
    Author: Glogowska M, Widdicombe JG.
    Journal: Acta Neurobiol Exp (Wars); 1973; 33(1):81-7. PubMed ID: 4698519.
    Abstract:
    In anaesthetized rabbits phenyl diguanide not only stimulates breathing (rapid shallow breathing) by a vagal reflex from lung J-receptors, but also causes a similar response in bilateral vagotomized animals. Injection of the drug into different parts of the circulation indicates that the main non-vagal response of breathing arises from areas supplied by the vertebral arteries, presumably in the brain.
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