These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Faecal bile-acids and clostridia in patients with cancer of the large bowel.
    Author: Hill MJ, Drasar BS, Williams RE, Meade TW, Cox AG, Simpson JE, Morson BC.
    Journal: Lancet; 1975 Mar 08; 1(7906):535-9. PubMed ID: 47015.
    Abstract:
    Of 44 patients with cancer of the large bowel, 36 ( 82%) had high faecal bile-acid concentrations compared with only 15 (17%) out of 90 patients with other diseases. 31 (70%) of the 44 patients with large-bowel cancer had high faecal bile-acid concentrations in the presence of faecal clostridia able to dehydrogenate the bile-acid nucleus, compared with only 8 (9%) out of 90 patients with other diseases. Thes findings support the hypothesis that cancer of the large bowel is caused by high concentrations of bile-acid derivatives produced by certain anaerobic bacteria.
    [Abstract] [Full Text] [Related] [New Search]