These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Acute renal failure associated with combined gentamicin and cephalothin therapy.
    Author: Fillastre JP, Laumonier R, Humbert G, Dubois D, Metayer J, Delpech A, Leroy J, Robert M.
    Journal: Br Med J; 1973 May 19; 2(5863):396-7. PubMed ID: 4703097.
    Abstract:
    Three patients with normal renal function developed acute renal failure between the ninth and twenty-seventh days of combined gentamicin and cephalothin therapy. The dose of gentamicin (4-6 mg/kg/day) was in the normal range, but that of cephalothin (180 mg/kg/day) was abnormally high. The nephropathy was of the tubular-interstitial type and the clinical picture similar to that seen in acute drug-induced nephropathies. Frusemide was given only after the onset of renal failure. In these three patients the high intravenous doses of cephalothin combined with gentamicin were probably nephrotoxic.
    [Abstract] [Full Text] [Related] [New Search]