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  • Title: Isotachysterol-3 and 25-hydroxyisotachysterol-3: analogs of 1,25-dihydrox vitamin D3.
    Author: Holick MF, DeLuca HF, Kasten PM, Korycka MB.
    Journal: Science; 1973 Jun 01; 180(4089):964-6. PubMed ID: 4706686.
    Abstract:
    Isotachysterol(3), 25-hydroxyisotachysterol(3), and isovitamin D(3) have been synthesized and tested for biological activity. Like 1,25-dihydroxyvitamin D(3), isotachysterol(3) stimulates intestinal calcium transport and bone calcium mobilization in anephric rats, whereas 25-hydroxyvitamin D(3) does not. Although isovitamin D(3) is biologically active in normal rats it is inactive in anephric rats.
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