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  • Title: Reduction of absorption of paracetamol by activated charcoal and cholestyramine: a possible therapeutic measure.
    Author: Dordoni B, Willson RA, Thompson RP, Williams R.
    Journal: Br Med J; 1973 Jul 14; 3(5871):86-7. PubMed ID: 4717848.
    Abstract:
    The absorption of an oral 2-g dose of paracetamol was markedly reduced by the simultaneous oral administration of either activated charcoal or cholestyramine but was only slightly reduced when the adsorbents were given 60 minutes after the paracetamol. Since the absorption of a larger dose of the drug will probably be slow, the administration of adsorbents may be of value even when delayed several hours.
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