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  • Title: Relative distribution of arylsulphatases A and B in rat liver parenchymal and other cells.
    Author: Hook GE, Dodgson KS, Rose FA, Worwood M.
    Journal: Biochem J; 1973 May; 134(1):191-5. PubMed ID: 4723221.
    Abstract:
    The relative activities of arylsulphatases A and B were measured in rat liver parenchymal and non-parenchymal cells, in peritoneal macrophages and in a number of rat tissues. Although absolute values cannot be obtained, it was shown that the arylsulphatase B/arylsulphatase A activity ratio is much higher in non-parenchymal cells than in parenchymal cells. The ratios in adrenals, brain and testis are very similar to each other but differ from those found in spleen, kidney and liver. These ratio variations may be caused by alterations in the activity of the B enzyme rather than the A enzyme. The relatively high B enzyme/A enzyme ratios in all rat tissues explains why the method devised for the independent assay of human arylsulphatases A and B cannot be employed with rat tissues.
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