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  • Title: Meiotic maturation in Xenopus laevis oocytes initiated by insulin.
    Author: El-Etr M, Schorderet-Slatkine S, Baulieu EE.
    Journal: Science; 1979 Sep 28; 205(4413):1397-9. PubMed ID: 472755.
    Abstract:
    Insulin can induce meiotic division in Xenopus laevis oocytes. This effect shows the specificity expected of a receptor-mediated mechanism. It is potentiated by ethynylestradiol, a steroid antagonist of pregesterone (the natural hormone that provokes meiosis). The Xenopus laevis oocytes may serve as a model for the study of the poorly understood effect of insulin on cell division.
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