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  • Title: Regulation of muscle acetylcholine sensitivity by muscle activity in cell culture.
    Author: Cohen SA, Fischbach GD.
    Journal: Science; 1973 Jul 06; 181(4094):76-8. PubMed ID: 4736607.
    Abstract:
    Muscle in tissue culture provides a good system for studying longterm changes in surface membrane acetylcholine sensitivity. Muscle fibers stimulated intermittently over prolonged periods are less sensitive to iontophoretically applied acetylcholine and bind less (125)I-labeled alpha-bungarotoxin than inactive fibers.
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