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  • Title: Ornithine decarboxylase activity and polyamine content of normal and fluoride resistant LS cells.
    Author: Hongslo JK.
    Journal: Acta Pharmacol Toxicol (Copenh); 1979 Jul; 45(1):32-5. PubMed ID: 474156.
    Abstract:
    The activity of ornithine decarboxylase (ODC) in suspension cultures of mouse fibroblasts, LS cells, varied in a characteristic cyclic pattern after dilution of the cultures. Two strains of fluoride resistant LS cells, FR6 and LSFR6 cells, exhibited the same cyclic pattern, but with markedly higher ODC activities. These fluoride resistant cells, however, contained less putrescine, the product of the ODC reaction. Possible reasons for this finding are discussed.
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