These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Lymphoblast proliferation and humoral antibody response after rubella vaccination.
    Author: Lalla M, Vesikari T, Virolainen M.
    Journal: Clin Exp Immunol; 1973 Oct; 15(2):193-202. PubMed ID: 4762016.
    Abstract:
    Twenty-eight sero-negative young women were vaccinated with RA 27/3 or HPV-77/DE5 strain live attenuated rubella vaccine. Haemagglutination-inhibiting antibody developed in all but one of the subjects. Rubella-specific IgM antibodies were demonstrable 3–6 weeks after vaccination. Complement-fixing and platelet-aggregation antibodies were more often detectable after RA 27/3 than after HPV-77/DE5 vaccination. After vaccination the blood lymphoblast count increased with a peak at 2 weeks. In one subject no humoral antibody response was detectable but even in this case there was a lymphoblast response. A marked increase in blasts was detected in a single case of natural rubella infection. In the vaccinated subjects the tuberculin skin test did not reveal suppression of delayed hypersensitivity 3 weeks after vaccination, nor was there a change in the responsiveness of lymphocytes to PHA in vitro 2 weeks after vaccination. No significant decrease in platelet count was seen in any of the subjects.
    [Abstract] [Full Text] [Related] [New Search]