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  • Title: Effect of chronic hypo and hypervitaminosis C on the brush border enzymes and the intestinal uptake of glucose and alanine.
    Author: Mahmood A, Chauhan VP, Lyall V, Sarkar AK.
    Journal: Experientia; 1979 Aug 15; 35(8):1057-8. PubMed ID: 477873.
    Abstract:
    Brush border sucrase and alkaline phosphatase activities are considerably enhanced in the intestine of ascorbic acid deficient guinea-pigs. Similar increase in the uptake of D-glucose and L-alanine also occurs in chronic vitamin C deficiency. However the permeability of D-glucose and L-alanine in the intestine of animals fed with large doses of vitamin C is severely depressed, with a reduction in the levels of sucrase and alkaline phosphatase activities.
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