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  • Title: Surgery of congenital heart disease assessed by radionuclide scintigraphy.
    Author: Gates GF, Orme HW, Dore EK.
    Journal: J Thorac Cardiovasc Surg; 1975 May; 69(5):767-75. PubMed ID: 47940.
    Abstract:
    Intravenous injection of 99mTc-labeled macroaggregated albumin (MAA) followed by lung and whole-body scintigraphy results in data from which magnitude of right-to-left shunting and distribution of pulmonary arterial blood flow can be calculated. This information is useful in assessing the functional capacity of a surgical systemic-pulmonic anastomosis. Malfunctioning anastomoses do not significantly reduce right-to-left shunting and may cause unilateral pulmonary hyperperfusion. However, preferential nuclide accumulation may occur in either lung, regardless of shunt function. Consequently, the degree of right-to-left shunting must be determined to fully assess a surgical anastomosis. This technique also allows for assessment of the reduction of right-to-left shunting after intracardiac repairs of congenital cardiac abnormalities.
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