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  • Title: [The role of serotonin and catecholamines in the regeneration of the Planaria Polycelis tenvis].
    Author: Franquinet R.
    Journal: J Embryol Exp Morphol; 1979 Jun; 51():85-95. PubMed ID: 479750.
    Abstract:
    During traumatic regeneration of Planaria Polycelis tenuis, determination of serotonin, noradrenaline and dopamine levels revealed important variations of serotonin and catecholamines from the time of excision. The use of specific inhibitors of these hormones delayed regeneration whereas simultaneous addition of an hormone and its antagonist restores a standard time of regeneration. Serotonin acts through adenylate cyclase system. Results allow us to assume that dopamine acts through the same mechanism. The action of noradrenaline is so far not elucidated although propranolol (beta antagonist) delays or inhibits completely regeneration.
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