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  • Title: Interruption of pregnancy by PGF 2 alpha. II. Extraovular administration.
    Author: Szontágh FE, Bártfai G, Herczeg J, Mészáros J.
    Journal: Acta Eur Fertil; 1973 Mar; 4(1):23-30. PubMed ID: 4804563.
    Abstract:
    The prostaglandin PGF2alpha was administered extraovularly to 38 health women aged 17-37 to induce abortion. The women were in the first trimester of pregnancy. The prostaglandin was given every 2nd hour in doses of 250-1000 mcg, depending on the frequency and intensity of the uterine contractions and on the side effects. Abortion took place within 36 hours (mean, 21.6 hours) in 26 (68.4%) of the cases. The quantity of PGF2alpha administered was 2.25-14.75 mg, with an average of 6.72 mg. Side effects (most notably, vomiting and diarrhea) occurred in 27 cases, but they did not interrupt the intermittent PG treatment. No essential changes in the results of laboratory tests were noted.
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