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  • Title: Immunological evaluation of a streptococcal preparation (OK-432) in treatment of bladder carcinoma.
    Author: Kagawa S, Ogura K, Kurokawa K, Uyama K.
    Journal: J Urol; 1979 Oct; 122(4):467-70. PubMed ID: 480487.
    Abstract:
    When 21 patients with bladder cancer (transitional cell carcinoma) were given local and systemic injections of a streptococcal preparation, OK-432, tumor regression was observed in 3 cases (14.3%). The marked infiltration of lymphocytes observed on histological examination of regressed tumors suggested that a host-mediated action was involved in the antitumor effect of OK-432.
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