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  • Title: Calcium absorption and calcium-binding protein synthesis: solanum malacoxylon reverses strontium inhibition.
    Author: Wasserman RH.
    Journal: Science; 1974 Mar 15; 183(4129):1092-4. PubMed ID: 4812040.
    Abstract:
    The ingestion of diets containing high concentrations of stable strontium inhibits calcium absorption and intestinal calcium-binding protein synthesis and, as shown by others, does so by inhibiting the conversion of 25-hydroxycholecalciferol to 1,25-dihydroxycholecalciferol, the active form of vitamin D. The addition of the South American plant Solanum malacoxylon to strontium-containing diets counteracts the inhibitory action of dietary strontium, thereby indicating that the plant contains a factor which can mimic the action of 1,25-dihydroxycholecalciferol and representing the first such factor identified in a botanical source.
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