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  • Title: Regulation of amino acid transport in kidney cortex of newborn rats.
    Author: Reynolds R, Rea C, Segal S.
    Journal: Science; 1974 Apr 05; 184(4132):68-9. PubMed ID: 4815284.
    Abstract:
    After incubation at 37 degrees C the subsequent uptake of alpha-aminoisobutyric acid, cycloleucine, glycine, and L-proline by newborn (as compared to adult) rat kidney cortex slices is enhanced. The effect is abolished by the presence of cycloheximide, actinomycin D, and high concentrations of the above-mentioned amino acids in the medium during the 37 degrees C incubation prior to measurement of uptake. The data suggest that there is an adaptive control mechanism which is expressed on incubation at 37 degrees C and which can regulate amino acid transport in newborn rat kidney cortex.
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