These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Folic acid absorption, anticonvulsant and contraceptive therapy.
    Journal: Nutr Rev; 1974 Feb; 32(2):39-41. PubMed ID: 4817610.
    Abstract:
    Studies of the effects of oral contraceptives and other drugs on folic acid absorption are reviewed. In 1 study, estradiol, progesterone, and estrone did not inhibit folate conjugase nor interfere with the passage of folate conjugase across the lysosomal membrane. 12 women taking an oral contraceptive (norethisterone and ethinyl estradiol) had significantly higher mean serum folate levels at Day 20 of the menstrual cycle than at Day 5 (7.63 ng/ml and 5.36 ng/ml), though no significant difference was observed with compared with a control group. In another study, women taking oral contraceptives showed significantly lower mean peak serum folate levels after saturation with yeast polyglutamate when compared with controls. It is suggested that steroid hormones increase the rate of clearance of folate from the blood.
    [Abstract] [Full Text] [Related] [New Search]