These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Alpha-hydroxyacid oxidase genetics in the mouse: evidence for two genetic loci and a tetrameric subunit structure for the liver isozyme.
    Author: Duley J, Holmes RS.
    Journal: Genetics; 1974 Jan; 76(1):93-7. PubMed ID: 4818266.
    Abstract:
    We have examined a polymorphism for liver GOX in inbred strains of the mouse Mus musculus. Genetic studies demonstrated that the two phenotypes for this enzyme present in BALB/C and NZC parental strains segregated as though they were controlled by codominant alleles at a single autosomal locus (GOX) which mapped closely to the agouti locus in linkage group V. Kidney HAOX activity is invariant in these inbred strains and is encoded by a separate genetic locus designated HAOX. BALB/C x NZC F(1) hybrid mice exhibited three intermediate forms of liver GOX activity, in addition to the parental enzymes, which is consistent with a tetrameric subunit structure.
    [Abstract] [Full Text] [Related] [New Search]