These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Effect of butyldiiodohydroxybenzoate on pituitary-thyroid interplay.
    Author: Iwasa Y, Tsukui T, Kanno Y, Koizumi Y, Kojima A, Yamada T.
    Journal: Proc Soc Exp Biol Med; 1975 Apr; 148(4):1167-72. PubMed ID: 48263.
    Abstract:
    The effect of BHDB, an analogue of thyroxine, on the pituitary-thyroid system was studied in the rat. BHDB produced low plasma T4 and T3 concentrations similar to those produced by methimazole, but failed to elevate plasma TSH and to produce goiter because of displacement of T4 from the binding protein. Low plasma thyroid hormone concentrations were due to an increase of fecal loss of thyroid hormones. By releasing excess iodide, BHDB blocked the development of goiter produced by methimazole.
    [Abstract] [Full Text] [Related] [New Search]