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Title: Prenatal detection of neural tube defects. Comparison between alpha-fetoprotein and beta-trace protein assays. Author: Milunsky A, Macri JN, Weiss RR, Alpert E, McIsaac DG, Joshi MS. Journal: Am J Obstet Gynecol; 1975 Jun 01; 122(3):313-5. PubMed ID: 48343. Abstract: The prenatal diagnosis of neural tube defects is now possible in about 90 per cent of cases by assaying the amniotic fluid for alpha fetoprotein. The accuracy of beta-trace protein assays on amniotic fluid samples from defective fetuses was compared to alpha-fetoprotein studies. At present, alpha-fetoprotein studies provide more reliable results.[Abstract] [Full Text] [Related] [New Search]