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  • Title: The nature and significance of hyperamylasemia follwing operation.
    Author: Morrissey R, Berk JE, Fridhandler L, Pelot D.
    Journal: Ann Surg; 1974 Jul; 180(1):67-71. PubMed ID: 4835959.
    Abstract:
    Total serum amylase activity was found to be significantly elevated postoperatively in 11 (10%) of 110 patients undergoing various surgical procedures. Isoamylase analysis revealed that the rise was chiefly in the pancreatic-type isoamylase in seven of the 11 patients showing postoperative serum amylase elevations; in the other four patients, the elevation occurred principally in the salivary-type isoamylase. These data demonstrate that postoperative hyperamylasemia occurs surprisingly often and that serum amylase activity may rise even when the surgical procedure is extra-abdominal. Moreover, elevation of serum amylase activity after surgery is not necessarily an indication of pancreatitis and may reflect instead a rise in salivary-type isoamylase.
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