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  • Title: Cold agglutinin autoimmune hemolytic anemia in nonhematologic malignancies.
    Author: Wortman J, Rosse W, Logue G.
    Journal: Am J Hematol; 1979; 6(3):275-83. PubMed ID: 484548.
    Abstract:
    Four patients with nonhematologic malignancies had the simultaneous finding of hemolytic anemia due to high-titer cold agglutinins. In each patient, the cold agglutinin had "anti-I" specificity and was of the IgM kappa immunoglobulin class. Although patients with hematologic malignancies not uncommonly have cold agglutinins, the association between these antibodies and nonhematologic malignancies is unusual.
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