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  • Title: Enhancement of pentagastrin-induced gastric acid secretion by clonidine in the conscious dog.
    Author: Curwain BP, Endersby K.
    Journal: Br J Pharmacol; 1974 Mar; 50(3):431-4. PubMed ID: 4851865.
    Abstract:
    The effect of intravenous clonidine on pentagastrin-induced gastric acid secretion has been studied in conscious dogs with Heidenhain pouches. Dose-dependent enhancement of secretion was found in response to clonidine (5-20 mu/kg). Clonidine (20 mug/kg) increased the maximal secretory rate to pentagastrin to a value not significantly different from the maximal response to histamine.
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