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  • Title: Mobility and the restriction of mobility of plasma membrane lectin-binding components.
    Author: Nicolson GL, Yanagimachi R.
    Journal: Science; 1974 Jun 21; 184(4143):1294-6. PubMed ID: 4857344.
    Abstract:
    Labeling by ferritin-conjugated agglutinins from Ricinus communis was used to demonstrate the relative mobilities of the agglutinin receptors located in specific regions on plasma membranes of rabbit spermatozoa. The relative mobility of lectin receptors was higher on postacrosomal regions of sperm than on acrosomal and tail regions. Lectin-induced clustering could not be demonstrated in the acrosomal and tail regions, an indication of the existence of localized restraints on the mobilities of lectin receptors. A system of transmembrane restraints may maintain the segregation of plasma membrane components into membrane domains on certain highly differentiated cells.
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