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  • Title: In vitro estimation of the proliferative state of murine bone marrow "colony forming units in culture" (CFUc) with hydroxyurea (HU).
    Author: Ujj G, Kovács P, Hernádi F.
    Journal: Biomedicine; 1979 Jun; 31(3):61-2. PubMed ID: 486692.
    Abstract:
    Exposure of CFUc to 1.0 mM of HU for two hours was at the plateau of both the dose--and time--respose curves, killing 38% of the CFUc. This is compatible with the result of the 3HTdR "suicide" method, a standard procedure for the estimation of the proportion of CFUc being in the S phase.
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