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  • Title: Abnormal leucocyte composition and sodium transport in essential hypertension.
    Author: Edmondson RP, Thomas RD, Hilton PJ, Patrick J, Jones NF.
    Journal: Lancet; 1975 May 03; 1(7914):1003-5. PubMed ID: 48673.
    Abstract:
    Cation transport and electrolyte composition were studied in leucocytes from 17 patients with uncomplicated essential hypertension. Significant increases in cell sodium and water contents, associated with a depression of the rate-constant for active sodium efflux, were found in the hypertensive patients. These abnormalities in cell sodium transport may possibly be related to mechanisms of hypertension.
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