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  • Title: Genetic map position of the gluconate-6-phosphate dehydrogenase gene in Salmonella typhimurium.
    Author: Murray ML, Klopotowski T.
    Journal: J Bacteriol; 1968 Apr; 95(4):1279-82. PubMed ID: 4869214.
    Abstract:
    Gluconate-6-phosphate dehydrogenase (GND) is genetically determined in Salmonella typhimurium by a locus (gnd) mapping between the somatic antigen (rfb) and histidine (his) operons. The enzyme is constitutive. Strains of Salmonella carrying an F' genetic element which contains the gnd(+) gene have GND activity two to three times that of the wild type. This gene dosage effect was used to determine that the GND reaction is not rate-limiting for the metabolism of glucose by the pentose shunt in S. typhimurium.
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