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  • Title: [Effect of cyclophosphane on the function and structure of the kidneys].
    Author: Castillo Herrero LM.
    Journal: Farmakol Toksikol; 1979; 42(5):523-5. PubMed ID: 488328.
    Abstract:
    In experiments on dogs and rats it has been shown that single administration of cyclophosphane in low doses produces no changes in the renal function or in water-electrolyte metabolism. Material changes in the canalicular apparatus of the kidneys, water-salt equilibrium and organ ultrastructure have been recorded in prolonged administration of the drug.
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