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  • Title: Erythromycin-resistant mutant of Escherichia coli with altered ribosomal protein component.
    Author: Tanaka K, Teraoka H, Tamaki M, Otaka E, Osawa S.
    Journal: Science; 1968 Nov 01; 162(3853):576-8. PubMed ID: 4886608.
    Abstract:
    Erythromycin combines with 50S ribosomal subunit of an erythromycin-sensitive Escherichia coli (strain Q13), while ribosomes from an erythromycin-resistant mutant from this strain have little affinity for the antibiotic. A protein component of the 50S subunit of the mutant strain is distinct from that of the parent Q13 strain.
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