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  • Title: Glomerulonephritis associated with polymyositis.
    Author: Dyck RF, Katz A, Gordon DA, Johnson M, Shainhouse Z, Cardella CJ, Bear RA.
    Journal: J Rheumatol; 1979; 6(3):336-44. PubMed ID: 490528.
    Abstract:
    Five patients with primary idiopathic polymyositis developed proteinuria associated with urine sediment abnormalities. Renal biopsies disclosed a focal mesangial proliferative glomerulonephritis with deposits of immunoglobulin and complement. After treatment of the polymyositis with corticosteroids, proteinuria and urine sediment changes disappeared within 4 to 8 wk along with an improvement in the muscle disease. Although the pathogenesis remains to be determined, immune complexes may be implicated in the etiology of this renal lesion.
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