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  • Title: [Effect of hypoxia on water-electrolyte metabolism and human renal function with different degrees of motor activity].
    Author: Grigor'ev AI, Korol'kov VI, Kozyrevskaia GI, Dotsenko MA.
    Journal: Kosm Biol Aviakosm Med; 1979; 13(5):10-4. PubMed ID: 491526.
    Abstract:
    It was demonstrated that a prolonged (24 days) bed rest at altitudes of 2200 m and 3200 m as well as at sea level was accompanied by an increased renal excretion of fluids and osmotically active substances, including electrolytes. Exercises done during bed rest indiced a smaller increase of the renal excretion of sodium and potassium. However, as bed rest continued the differences between the groups of test subjects disappeared. The levels of hypoxia and exercises used in the study proved inefficient to prevent changes in the fluid-electrolyte metabolism occurring during bed rest.
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