These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
Pubmed for Handhelds
PUBMED FOR HANDHELDS
Search MEDLINE/PubMed
Title: Vascular lesions: possible pathogenetic basis of the generalized Shwartzman reaction. Author: Gaynor E, Bouvier C, Spaet TH. Journal: Science; 1970 Nov 27; 170(3961):986-8. PubMed ID: 4920033. Abstract: Evidence of vascular injury was found in rabbits after a single small dose of endotoxin from Escherichia coli. Eighty percent of the treated animals developed circulating endothelial cells, leukopenia, and thrombocytopenia, and 50 percent had aortic endothelial lesions as determined by electron microscopy. Prior anticoagulation with heparin did not prevent this response. No control animals showed these abnormalities.[Abstract] [Full Text] [Related] [New Search]