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  • Title: Kidney biopsy in the hepatosplenic form of infection with Schistosoma mansoni in man.
    Author: da Silva LC, de Brito T, Camargo ME, de Boni DR, Lopes JD, Gunji J.
    Journal: Bull World Health Organ; 1970; 42(6):907-10. PubMed ID: 4920546.
    Abstract:
    A study of early glomerular lesions was made in 8 patients infected with Schistosoma mansoni but having no clinical evidence of renal disease. Electron-microscopy of renal biopsies showed the presence of electron-dense deposits in basement membranes and of laminated bodies near the mesangial cells. Immunofluorescence showed that the deposits corresponded to IgG in 8 cases and to IgM in 2 cases. These lesions are comparable with those found in the kidneys of patients with cirrhosis of the liver.
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