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Title: Defective recovery of semi-conservative DNA synthesis in xeroderma pigmentosum cells following split-dose ultraviolet irradiation. Author: Moustacchi E, Ehmann UK, Friedberg EC. Journal: Mutat Res; 1979 Aug; 62(1):159-71. PubMed ID: 492196. Abstract: In normal human fibroblasts we observe an enhancement of the recovery of the rate of semi-conservative DNA synthesis after split-dose UV-irradiation relative to a single total UV dose. The enhanced recovery is totally absent in both a xeroderma pigmentosum variant line and two xeroderma pigmentosum lines belonging to complementation groups A and C.[Abstract] [Full Text] [Related] [New Search]