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  • Title: Allotypic suppression of adult mouse spleen cells.
    Author: Anderson HR.
    Journal: Immunology; 1970 Jul; 19(1):169-79. PubMed ID: 4922028.
    Abstract:
    Adult mouse spleen cells were transferred into irradiated adult mice with xenogeneic erythrocytes. Antibody-producing cells were measured by the localized haemolysis in gel (LHG) assay. Anti-allotype serum directed against the γG2a allotype of the donor cells, given to the recipients at the same time as antigen and spleen cells, suppressed the plaque-forming cells (PFC) producing antibody of that allotype, and had little effect on the other classes investigated.
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