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  • Title: Chromosomal integration of F' factors in recombination-deficient Hfr strains of Escherichia coli.
    Author: DeVries JK, Maas WK.
    Journal: J Bacteriol; 1971 Apr; 106(1):150-6. PubMed ID: 4928006.
    Abstract:
    In matings between F' donors and recombination-deficient Hfr recipients, we isolated progeny which transferred both episomal markers and Hfr markers early and with high frequency. A number of these progeny had two integrated sex factors. Investigation of these double Hfr strains showed that the F' nearly always integrated in a homologous region of the chromosome. In any particular mating system integration was specific as to location and direction of chromosome transfer.
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