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Title: The genetic basis of autoimmunity in NZB mice studied by progeny-testing. Author: Ghaffar A, Playfair JH. Journal: Clin Exp Immunol; 1971 Mar; 8(3):479-90. PubMed ID: 4930642. Abstract: NZB mice were mated to NZW and to Balb/c, and the F1, F2 and backcross progeny tested for the incidence of red-cell autoantibodies, glomerulonephritis, and anti-nuclear antibodies. Evidence was found for some segregation of these autoimmune characteristics, and the results were interpreted as favouring an underlying genetic basis, though not a simple one.[Abstract] [Full Text] [Related] [New Search]